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New drug to combat Mesothelioma |
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| A new drug to help treat patients diagnosed with a devastating form of
cancer will be available within months, according to its makers. Alimta is set to be commercially
available by the beginning of next year for people with Mesothelioma, a rare cancer of the lung
lining usually caused by exposure to asbestos. The drug, also known as Pemetrexed, is the first
licensed treatment for malignant pleural mesothelioma, in combination with Cisplatin, makers
Lilly UK said today. |
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| The cancer has no known cure, gand Professor Hilary Calvert, of the Northern
Institute of Cancer Research, at the University of Newcastle upon Tyne, said: "This form of cancer is
usually diagnosed at an advanced stage at which point treatment with radiation therapy or surgery is
not an option. Most of the patients I see only have a life expectancy after diagnosis of only a matter
of months." |
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Mesothelioma Treatment breakthrough |
| Until now there has been no licensed chemotherapy available and patients
have been more likely to have treatment aimed to relieve the symptoms rather than to
control the disease. |
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| Alimta was licensed in February by the American Food and Drug Administration,
which said patients lived, on average, nine to 13 months following diagnosis. |
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| Patients given Alimta and cisplatin lived three months longer than those on
cisplatin alone. The trials of Alimta have also seen a shrinking in the size of the tumour,
thereby improving patients' quality of life, a spokeswoman for Lilly added. |
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| It is estimated that in the UK more that 1,700 people are diagnosed with
mesothelioma every year, decades after exposure to asbestos, and the numbers are set to peak at up to
2,500 in 2015. |
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| Previously, those most at risk of exposure to asbestos were in industries
such as shipbuilding, mining, and railway engineering. Areas of high incidence include London,
Glasgow, Newcastle, Greater Manchester, Plymouth and Hampshire. Earlier this year, the Government was
warned deaths from asbestos-related diseases were reaching "epidemic" levels by a law firm which said
it was dealing with hundreds of claims for people with mesothelioma. |
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| Asbestos was banned in the UK in 1999, but has been used in a variety of
products over the years, ranging from gas masks and ironing boards to roofing materials and pipe
lagging. The drug was licensed in the UK earlier this year. A spokesman for the Department of Health
in the UK said officials were unavailable for comment. |
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